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Once discovered and established as therapeuti c agent, the drug substance is used for pharmacotherapy of various diseases. The drug substance itself has unique properties, which in certain cases do not allow for effective therapy. This is the area, where pharmaceutical technology allows to improve drug substance original characteristics by optimization of pharmaceutica l formulation. The latter is a complicated process involving many variables concerning formulation qualitative and quantitative composition as well as technology parameters. This chapter will be de dicated to the computer systems based on artificial neural networks allowing for guided pharmaceutical formulation optimization.

Decision Support Systems for Pharmaceutical Formulation Development Based on Artificial Neural Networks