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Why nearly 200 years after the accidental discovery of natural iodine by Bernard Courtois (Dijon, France, 1811) are researchers still intrigued by this element? Why do they constantly search for more sensitive and reliable methods of its determination? During the last 200 years the status of research into the role of iodine in living organisms and the environment has progressed through many phases, from rapture over its interesting properties and healing powers to even some kind of “iodophobia”. According to the World Health Organization (WHO), an estimated 2 billion people, including 285 million school-age children, are iodine deficient. And among them, iodine deficiency disorders (IDD) affect some 740 million -with almost 50 million of them suffering from some form of brain damage resulting from iodine deficiency (United Nations Administrative Committee on Coordination/ Sub-Committee on Nutrition, 2000). On the other hand, it is known that large amounts of iodine are able to block the thyroid's ability to make hormones and worsen infiltration of the thyroid by lymphocytes. According to Teng’s studies (Teng et al., 2009) giving iodine to people who had adequate or excessive iodine intake increases the incidence of autoimmune thyroiditis.

A Review of Spectrophotometric and Chromatographic Methods and Sample Preparation Procedures for Determination of Iodine in Miscellaneous Matrices