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Nitric oxide (NO) is produced in the endothelial cells, neurons, glia, and macrophages by the nitric oxide synthase (NOS) isoenzymes. Endothelial nitric oxide synthase (eNOS) is a subgroup of this family of enzymes that catalyze the production of nitric oxide (NO) from Larginine and oxygen, which causes vascular relaxation (1) by activates guanylate cyclase, which induces smooth muscle relaxation.

Lack of Evidence for Contribution of eNOS, ACE and AT1R Gene Polymorphisms with Development of Ischemic Stroke in Turkish Subjects in Trakya Region