English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Lymphatic filariasis has an effect on almost 120 million individuals all over the world. The disease may cause a chronic morbidity if the persons who are infected are left untreated. It is endemic in many parts of tropical countries. To prevent worldwide parasite transmission, the World Health Organization initiated the Global Programme to Eliminate Lymphatic Filariasis (GPELF) by eliminating filarial parasites from their human hosts (Molyneux & Zagaria, 2002). Various GPELF implementations are done in many participating countries. In 2004 alone there were more than thirty countries have started elimination program and this number is still rising. Various degrees of success have emerged as a result of the implementation of this program. Although it was reported that in some places the program has interrupted the transmission, in many other places the program could not stop the transmission of the disease (WHO, 2005). It has been argued that strategic choices and operational or biological factors contribute to the success or failure of the program. In general, it is difficult to evaluate the success or the failure of a health program, especially in the beginning of the program. A mathematical model provides useful tools for planning and evaluation of control program in disease elimination (Goodman, 1994). In our earlier work (Supriatna et al., 2009) we develop a mathematical model for the transmission of Lymphatic Filariasis disease in Jati Sampurna, Indonesia. In Indonesia, the disease is already alarming. For example, the incidence of filariasis in Jati Sampurna (a district in the West Java province) is more than 1%. Within less than five years since the date of the publication confirming that Jati Sampurna is an endemic area, almost all regions nearby Jati Sampurna, and other relatively far distance areas are affected by the disease, and some of them are also categorized as endemic areas. Other cases of filarial prevalence are reported outside Java island, such as in Alor islands (the province of Nusa Tenggara Timur). On Alor islands, both B. timori and W. bancrofti are circulated, with a prevalence of up to 20% (Supali et al., 2002). Indonesia joined the GPELF since 2001 and implemented administration of a single dose regimen of diethylcarbamazine (DEC) and albendazole in endemic areas (Krentel et al., 2006). Our previous model tries to capture the effectiveness of this scenario in the attempt of controlling the spread of the disease, inspired by the transmission of the disease in Jati Sampurna. The model assumes that acute infected humans are infectious and treatment is given to a certain number of acute infected humans found from screening process. The screening is

Lymphatic Filariasis Transmission and Control: A Mathematical Modelling Approach