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Surface plasmon resonance (SPR) sensors provide high sensitivity without the use of molecular labels (Homola, Yee, and Gauglitz 1999). They been widely used in the analysis of biomolecular interactions (BIA) and detection of chemical and biological analytes (Homola, Yee, and Gauglitz 1999), where they provide benefits of real-time, sensitive and label-free technology. They have also been used for the detection of various chemical and biological compounds in areas such as environmental protection, food safety and medical diagnostics (Mouvet et al. 1997; Nooke et al. 2010).

A Novel Compact Photonic Crystal Fibre Surface Plasmon Resonance Biosensor for an Aqueous Environment