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Studies on the efficacy of antioxidant treatment in type 1 diabetes mellitus is an interesting, actual research subject. Reactive oxygen species (ROS) are continuously produced and eliminated by living organisms normally maintaining ROS at certain steady-state levels. Under some circumstances, the balance between ROS generation and elimination is disturbed leading to enhanced ROS level causing oxidative stress Lushchak, 2011. Oxidative stress is involved in the development of several important diseases (cancer, ulcer, atherosclerosis, autoimmune diseases, ischaemia-reperfusion injury, emphysema, inflammation, etc.).

Evaluation of Oxidative Stress and the Efficacy of Antioxidant Treatment in Diabetes Mellitus