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Lymphoproliferative disorders (LPDs) represent a heterogeneous group of expanding, monoclonal or oligoclonal, lymphoid cells that occur in the setting of immune dysfunction. They are sometimes equated with "immunoproliferative disorders", but technically LPDs are a subset of immunoproliferative disorders, along with hypergammaglobulinemia and paraproteinemias. Several inherited gene mutations have been identified to cause lymphoproliferative disorders. Acquired and iatrogenic causes are also responsible for the appearance of these diseases.

Animal Models of Lymphoproliferative Disorders Focusing on Waldenström's Macroglobulinemia