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With the advent of modified improved JE vaccines, JE preventive program is now going on in full swing throughout the globe, particularly in South-East Asian countries where the disease is highly prevalent. However, recent unswerving studies indicated that we should not satisfy ourselves with the belief that we could be able to stop the spread of this dreaded disease in near future. This is because as much as forty per cent infected children was found vaccinated questioning the efficacy of the vaccines itself, which are currently in use and frequent failures to access the deep rural areas, and in the vast forest areas by the dedicated trained vaccination team due to uninterrupted seasonal and other natural catastrophes which becomes a major setback in the program. Thus although almost all developing countries in the endemic zones have accepted the control program by vaccination, but the outcome of such an elaborate and difficult protocol appears gloomy. It is true that a speculative encouraging approach may not be practically feasible in a wide scale vaccination program considering the unreachable vast tropical rural areas and taming a gigantic inadequately educated population from aversion in participation in such a vaccination program.

The Role of 'Belladonna 200' in the Prevention of Japanese Encephalitis (JE) Virus Infection