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Active immunity refers to the process of exposing the body to an antigen to generate an adaptive immune response: the response takes days/weeks to develop but may be long lasting—even lifelong. Wild infection with pathogenic agents (eg. Hepatitis A Virus) and subsequent recovery gives rise to a natural active immune response usually leading to lifelong protection. In addition, some infections can be prevented by immunization with vaccines.

Recombination and Point Mutations in Type G Rotavirus Strains: The Challenges of Vaccine Development