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Malaria remains a devastating disease, particularly in the tropics. The annual incidence of malaria worldwide is estimated to be between 294 and 500 million clinical cases, while estimates of annual mortality from malaria, caused largely by the protozoan Plasmodium falciparum, range from 0.97 to 2.7 million worldwide (World Malaria Report 20101, World Health Organization; Snow et al., 2005). The emergence of resistance to conventional antimalarial drugs and insecticides means that new chemotherapeutic approaches with alternative targets are needed (Ridley, 2002). Better understandings of antimalarial drugs and the biology of the parasites are needed to allow the development of new medications.

Intraerythrocytic Plasmodium falciparum Growth in Serum-Free Medium with an Emphasis on Growth-Promoting Factors