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The World Health Organization (WHO, 2003, 2011) estimated that at international level approximately 1.3 million people currently smoke cigarettes or other products. Almost one billion men and 250 million women, and about 6 million people die each year from diseases related to smoking. Related diseases comprise different types of cancer (lung, larynx, oral cavity), cardiovascular (atherosclerosis, stroke), respiratory diseases (acute and chronic), alterations in the reproductive system, dental problems (leukoplakia, gingivitis, among others), peptic ulcer and some diseases of eye, diabetes.

Motivational Intervention and Nicotine Replacement Therapies for Smokers: Results of a Randomized Clinical Trial