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The incidence of cranial nerve (CN) palsy is not uncommon in patients with untreated nasopharyngeal cancer (NPC). In the 7th edition of the American Joint Committee on Cancer (AJCC) Staging Manual, the AJCC recommended that CN involvement be assessed by neurological evaluation rather than by cross-sectional imaging (computed tomography [CT] and magnetic resonance imaging [MRI]), because CN involvement is considered a poor prognostic indicator in NPC patients, those with CN involvement are staged as T4.

MRI-Detected Cranial Nerve Involvement in Nasopharyngeal Carcinoma