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Osteoporosis is defined as a skeletal disorder characterized by loss of bone mass, decreased bone strength and resulting in increased risk of bone fracture. The disease is progressive with age, especially in postmenopausal women [1]. Osteoporotic hip fractures and vertebral fractures have become a major social problem because the elderly population continues to increase. Hip fractures account for about 10% of all osteoporosis-related fractures [2]. Hip fractures are particularly devastating and have a particularly negative impact on morbidity. Survivors often suffer severe and prolonged physical and social limitations, and fail to recover normal activity [3]. Vertebral fractures affect approximately 25% of postmenopausal women [4]. Vertebral fractures can be associated with chronic disabling pain and incur loss of normal activity.

Ex Vivo and In Vivo Assessment of Vertebral Strength and Vertebral Fracture Risk Assessed by Dual Energy X-Ray Absorptiometry