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Positron emission tomography (PET) is a three-dimensional nuclear medicine imaging technique that provides metabolic information about the body. This technique was first introduced by Kuhl et al. (Kuhl, Chamberlain et al. 1956). The basic principle of this system is to detect pairs of gamma rays emitted indirectly by a positron-emitting radionuclide (tracer), which is introduced into the body on a biologically active molecule. The metabolic information as three-dimensional imaging is obtained from the positional information of the tracer, obtained by computer analysis of the gamma rays. The metabolic information obtained is considered a functional imaging technique, whereas computed tomography (CT) and magnetic resonance imaging (MRI) are regarded as morphologic imaging techniques. Moreover, the fusion of PET with CT (PET-CT) has further elevated the precision of functional imaging techniques. Clinical applications of PET have increased in the last decade and have proven to be vital in the evaluation and diagnosis of diseases. The broad scope, versatility and sensitivity of PET make it the most powerful molecular imaging technique currently available for clinical use.

Potential of Positron Emission Tomography for Neurogenic Tumors and Spinal Disorders