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The objective of this chapter is to provide an overview of the different approaches that have been undertaken in our laboratory and by other researchers to investigate the different aspects of snake venoms using two-dimensional electrophoresis (2DE). It will also highlight the few novel modifications that we have employed to improve the protocol of 2DE, in order to further increase its versatility as a research tool in the study of snake venoms.

The Role of Conventional Two-Dimensional Electrophoresis (2DE) and Its Newer Applications in the Study of Snake Venoms