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Cervical cancer is still one of the leading cancers worldwide (1), although there is a discrepancy between developed and developing countries. In developed countries, there is a continuous decline in incidence and mortality, whereas in developing countries, there is a more stable or even increasing pattern. The latter is more likely to be due to the lack of screening and infectious cofactors than to ethnic differences. Cervical cancer remains the only human malignancy that has been successfully reduced by medical intervention. Organised screening (OrS) for cervical cancer by the conventional Pap smear is the only means with proven efficacy of reducing the incidence and mortality of this disease in countries where it has been successfully implemented. According to the official statistics, the age standardized incidence rate of cervical cancer in Italy currently (2002) levels of at 8.1/100.000 with a mortality rate of 2.2/100.000 (2). Italy is another European country with no unified national screening programme, but each region has adopted a screening policy of its own. (3)Cervical cancer screening in Italy started as a spontaneous activity, with no national organization, which, not unexpectedly, led to incomplete population coverage. The Italian health system is managed by Italy’s 20 Regions (Figure 1).

Incidence of Invasive Squamous Cell Carcinoma Diagnosed with Opportunistic Screening in >70 Years-Old Women: Italy as a Case Study