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In the last decade, increasing interest in the role of nutrition in disease prevention has been observed. The World Health Organization (WHO) reported that one-third of all cancer deaths could be prevented, and that diet plays a key role in prevention (Bode & Dong, 2009). The term chemoprevention introduced and developed by Sporn (2005) and Wattenberg (1985) refers in general to multi-targeted pharmacological and nutritional intervention with the use of naturally occurring or chemically synthesized compounds. For this purpose, dietary phytochemicals believed to be safe for human use seem to be very promising. The importance of natural chemopreventive agents relies on their non-toxicity when given in small amounts for longer periods of time. Moreover, using a combination of phytochemicals provides synergistic or additive preventive effects.

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The Inhibitory Effect of Natural Stilbenes and Their Analogues on Catalytic Activity of Cytochromes P450 Family 1 in Comparison with Other Phenols - Structure and Activity Relationship