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An sEMG signal comprises what is otherwise termed a compound muscle action potential (CMAP) being the sum of any number of motor unit action potentials within a given recording area. However, just such an sEMG signal, which provides an insight into the level of activity of a given skeletal muscle, can be altered/affected in many ways by what have been defined as causative, intermediate and deterministic factors (De Luca, 1997). The causative factors include such parameters as the configuration of the recording electrodes (size, distance apart etc.), skin thickness and subcutaneous tissue composition and depth, blood flow, muscle fibre diameter and orientation as well as the number of active motor units within the muscle of choice and their firing rate one with another, that is to say their synchronization (De Luca, 1997). Added to these parameters are the intermediate factors which include the choice of using a differential electrode filter, the risk of cross-talk from adjacent muscles or underlying tissue, the occurrence of spatial filtering as a consequence of fibre depth, the volume of the muscle that is detectable, and the conduction velocity of muscle fibres. Finally, there are the deterministic factors which comprise the number of

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Clinical Implications of Muscle-Tendon &amp; -Force Interplay: Surface Electromyography Recordings of m. vastus lateralis in Renal Failure Patients Undergoing Dialysis and of m. gastrocnemius in Individuals with Achilles Tendon Damage