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Recent advances in biotechnology gave rise to a set of microarray technologies that became ubiquitous in research, medicine, and industry for tens of applications. Microarray technology has centered on providing platforms for analyzing, in a single experiment, tens or even hundreds of samples from different biologic sources. Its rapid and global adoption has been predicated on its simplicity and efficiency in quickly providing relevant data generated by simultaneous testing of biological samples with a large number of probes. In this chapter, we describe new microarray approaches that have considerably simplified the characterization of viral genes and genomes with specific emphasis on analysis of the genetic stability of live viral vaccines.

Microarray Techniques for Evaluation of Genetic Stability of Live Viral Vaccines