English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

This Chapter deals with bulk hydrogels consisting of a widely used biomaterial: poly(ethylene) glycol (PEG). PEG is renown for its bio-inertness; it is very effective in suppressing non-specific protein adsorption (NSPA) and thereby preventing cell adhesion. However, we have observed unexpected adhesion of fibroblast cells to the surface of bulk PEG hydrogels when the surface was decorated with micrometer-sized, topographic patterns. This Chapter describes the aim of our investigations to unravel the biophysical, biochemical and biomechanical reasons why these cells do adhere to the intrinsically antiadhesive PEG material when it is topographically patterned.

Cell Adhesion and Spreading on an Intrinsically Anti-Adhesive PEG Biomaterial