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Annually several million people suffer bone fractures caused by accidents or diseases. Many of those fractures are too complex for an external medical treatment but have to be surgically fixated by internal bone implants. Traditional methods of osteosynthesis or osteotomy use permanent metal implants e.g. bone screws and bone plates made of steel or titanium alloys, but permanent metal implants have to be excised. Especially young patients in growth require the implant removal. Usually, metal implants should be removed latest one or two years after the first surgery. Biodegradable implants, which dissolve in the human organism, therefore represent an appropriate solution. Here magnesium as a degradable implant material provides both biocompatibility and sufficient mechanical properties. Studies have shown that magnesium, which is an essential element of the human organism, is suitable as a degradable biomaterial for use in medical implants. Also in relation to biomechanical requirements the suitability of magnesium as an implant material in has already been proven. Due to mechanical properties superior to the bone, magnesium implants show biomechanical properties comparable to conventional steel implants in standardized biomechanical tests. Also an influence of surface properties on the degradation behavior is already known. Interdisciplinary research between medical and engineering sciences focuses on the development of degradable magnesium implants for osteosynthesis. The removal of those implants after convalescence of the fractured bone is no longer necessary, resulting in a considerable benefit for patients and the public health care system. The aim is to preset individual degradation kinetics for implants made of biocompatible magnesium alloys through adjusting surface and subsurface properties of the magnesium implants for specific indications. Adapted machining processes exhibit possibilities to adjust those properties. The idea of implants specifically adapted to their desired function and functional period within a possible range of surface or subsurface modifications is illustrated schematically in Figure 1for different implant designs (V1 and V2). The healing

Biocompatible Magnesium Alloys as Degradable Implant Materials - Machining Induced Surface and Subsurface Properties and Implant Performance