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Laparoscopy-assisted local injection of chemotherapeutic agents is not yet considered as a standard treatment for ectopic pregnancy. Herein, we demonstrated cases of cesarean scar pregnancy and ovarian ectopic pregnancy successfully treated with trans-vaginal sonography-guided local injection of etoposide. Furthermore, we evaluated the efficacy of laparoscopic local injection of etoposide compared with methotrexate on tubal pregnancy treatment. With the aid of laparoscopic injection, local etoposide treatment offers a precise localization and minimally invasive approach to the management of ectopic pregnancies. Compared to the conventional way to treat ectopic pregnancy using methotrexate, local injection of etoposide is considered to be a high-success rate, low-risk, and less-limitation option for such types of ectopic pregnancies with careful selection of cases.

The Treatment of Ectopic Pregnancy with Laparoscopy-Assisted Local Injection of Chemotherapeutic Agents