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Mitochondria are active intracellular structures that collide, divide, and fuse with other mitochondria. Mitochondria exist as branched-chain reticulum networks, but can also exist as punctuated structures. Their distribution within the cells is quite diverse, is regulated by the interactions with the cytoskeleton and maintained by the balance between mitochondrial fusion and fission. Mitochondria play crucial physiological functions that underlie the distortions of fragile balance between health and disease. In recent years, the role of mitochondria has gained much interest in the field of diabetic pathology since mitochondrial abnormalities were found in insulin resistance and in both types of diabetes.

Mitochondria Function in Diabetes – From Health to Pathology – New Perspectives for Treatment of Diabetes-Driven Disorders