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Medically intractable epilepsy is considered for surgical intervention first for resection of localized area of brain in which cases seizure control is expected generally. Nevertheless, those with non-localizing lesions in the imaging studies as well as multifocal spikes in electroencephalography (EEG) are not candidates for the resective surgery. For palliative intervention, corpus callosotomy may be considered for these patients. Early detection of proper candidates for surgical intervention in pediatric patients with medically intractable seizures may give a better chance of recovering their developmental potential by protecting the brain from further epileptic discharges.

Corpus Callosotomy in Pediatric Intractable Epilepsy: Microsurgical Technique Implication and Variation