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Pyoluteorin (Plt, 4,5-dichloropyrrol-2-yl 2,6-dihydroxyphenyl), a polyketide antibiotic produced by certain strains of Pseudomonas spp., including the rhizobacteria Pseudomonas fluorescens CHA0 (Maurhofer et al., 1992), Pseudomonas fluorescens Pf-5 (Corbell & Loper, 1995), Pseudomonas fluorescens S272 (Yuan et al., 1998) and Pseudomonas sp. M18 (Hu et al., 2005) et al., was first identified and separated by Takeda from Pseudomonas aeruginosa (Tekeda, 1958). Plt is a yellow crystal composed with a bichlorinated pyrrole linked to a resorcinol moiety (see Fig. 1), it can be completely dissolved in organic solvents such as methanol and chloroform (Wang et al., 2008). Plt can effectively inhibit phytopathogen fungi, including the plant pathogen Pythium ultimum, and suppress plant diseases caused by this fungus (Howell & Stipanovic, 1980; Maurhofer et al., 1992; Maurhofer et al., 1994). Moreover, in some instances, it contributes to the ecological competence of the producing strain within Rhizosphere (Howell & Stipanovic, 1980; Carmi et al., 1994; Yuan et al., 1998; Babalola, 2010).

The Production, Separation and Stability of Pyoluteorin: A Biological Pesticide