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Previous researches have implicated the close relationship between peroxiredoxin I (Prx I) and cancer progression. A lung adenocarcinoma-related human phage antibody library has been constructed by using phage display techniques. This study was to screen out the single chain variable fragment (scFv) antibodies from the library against a lung adenocarcinoma cell line overexpressing Prx I and to analyze their anti-proliferation ability.

aizheng/chinese journal of cancer

Inhibitory effect of novel internalized fully human phage antibody fragments on proliferation of lung adenocarcinoma cell line overexpressing peroxiredoxin I