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The strength and vitality of publications in our profession and pharmaceutical science disciplines are centered on the premise of a high-quality manuscript peer review process. Peer review is the essential element in promoting quality and excellence in the papers published in our scientific, educational, and professional journals. Peer review provides authors with the opportunity to improve the quality and clarity of their manuscripts. It also guides the journal's editorial staff in making publication decisions and identifying substandard manuscripts that should not be published. Individuals who participate in the peer review process provide a valuable service to their colleagues and the journal's editorial staff members by improving the literature in their discipline. Serving as a manuscript peer reviewer is an important, critical professional activity and responsibility.  New reviewers may not have been mentored by senior faculty members or gained experience by editing their colleagues' papers. In fact, when presented with the first opportunity to review a manuscript, most reviewers have neither received any instruction nor guidance in how to conduct a manuscript review nor is the process something that is easily mastered.1 The goal of this communication is to provide suggestions how to improve the quality of the peer review process and assist new reviewers with insights and guidelines for conducting a comprehensive, impartial, and fair review. Useful alternative resources for the new reviewer include the works of Provenzale and Stanley1 and Scheife and Cramer.2

Your Role and Responsibilities in the Manuscript Peer Review Process