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An acute damage of ultraviolet rays on skin, which was called sunburn, had already known in the ancient times. In recnt years it was reported that the phenomenon was resulted from direct DNA damage by UVB and that its action apectrum was in UVB. Furthermore the immunosuppression was shown to be elicited by UV. In addition to acute responses, chronic response by UV were called photoaging. Photoaging incloudes skin cancer, malignant melanoma, wrinkles , pigmented apots and sagging. They are induced by accumulation of DNA damages and generation of lipid peroxides and radicals by repeated UV exposure. However we don't know in detail which wavelength elicit these changes. In order to prevent our skin from photodamage, we have to take care of our life style , to wear hats and wears, and to apply sunscreen on our skin.

The Damage on the Skin Induced by UV Exposure in Sunlight