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We report a case of a giant epidermal cyst of the ear lobe. Epidermal cysts are commonly observed on the face, neck and upper back. To the best of our knowledge, there have been no reports of a giant epidermal cyst of the ear lobe. A 48-year-old female exhibited painless swelling on the left ear lobe, which progressed over a period of several years. The giant tumor was resected under general anesthesia. Histopathology confirmed the diagnosis of a typical epidermal cyst. Epidermal cysts are thought to result from the proliferation of surface epidermal cells or to originate in the infundibular hair sheath. In recent years, epidermal cysts of the ear lobe have been reported due to ear piercing, and it is of note that this epidermal cyst was of a markedly large size.

A Giant Epidermal Cyst of the Ear Lobe.