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Objectives: This study aims to compare the efficacy and complications of different medical treatment modalities used to prevent otorrhea following ventilation tube placement. Patients and Methods: This single-center, evaluator-blinded, controlled study included a total of 241 consecutive children (137 males, 104 females; mean age: 7.3±2.6 years; range, 3 to 13 years) who underwent bilateral ventilation tube placement due to bilateral serous otitis media between July 2014 and June 2016. The patients were classified according to the medical treatment protocols applied. Group 1 (n=56) received oral antibiotics; Group 2 (n=57) received oral antibiotics + local antibiotic ear drops; Group 3 (n=65) received local antibiotic ear drops; and Group 4 (n=63) received local antibiotic-glucocorticoid ear drops. Results: The lowest rate of otorrhea seen was 5.2% in Group 2, followed by 6.34% in Group 4. The highest rate of otorrhea was seen in Group 1. In the evaluation of the efficacy of the treatments, otorrhea was eliminated in Group 2 at a rate of 75% on Day 4. The same success rate was reached on Day 6 in Group 4 and on Day 12 in the other groups. The highest rate (28%) of side effects was seen in Group 2. Although the rates in the groups applied with local treatments were lower than those of the other groups, the difference was not statistically significant (p=0.051). Conclusion: The administration of local antibiotic-glucocorticoid ear drops can be considered an effective and safe treatment option with similar otorrhea and lower complication rates.

A comparison of different treatment modalities used as otorrhea prophylaxis following ventilation tube placement