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In addition, a dramatic decrease in secondary amyloidosis, the most serious complication of FMF, has been reported in Turkey in recent years. This can be attributed to the increased awareness of physicians with regard to FMF.[4] Familial Mediterranean fever was highlighted as a health problem due in large part to a study published in 1993 that reported on this disorder in Turkey.[5] In 1998, the high prevalence rate of FMF at 1/1.073 in a field study placed it as one of the most frequent genetic diseases in Turkey.[6] Subsequently, there have been increased efforts to train Turkish physicians regarding this inherited disorder. In 2005, a nationwide study on FMF further increased awareness and verified the need for healthcare professionals to become more familiar with it.[3] The main factor for the dramatic decrease in the cases of renal amyloidosis in Turkey is thought to be due to better medical education and practice among Turkish physicians which has led to the increased use of colchicine.[4]

The Rate of Awareness for Familial Mediterranean Fever for Urban Dwellers in Turkey