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EKOS EndoWave system is an ultrasound-accelerated catheter-directed thrombolysis device designed for the treatment of deep vein thrombosis. This system acts by emitting ultrasonic waves that enhance the diffusion of the simultaneously administered thrombolytic infusion inside the clot. EKOS operates inside the thrombosed veins and is categorized as such among the group of pharmaco-mechanical thrombolysis devices. In this article, we present a case of an iliac vein perforation and extravasation of the EKOS EndoWave system that has not been encountered in the current practice thus far.

Iliac vein perforation caused by an ultrasound-accelerated thrombolysis catheter: An unusual complication of EKOS EndoWave