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. The aim of this study is to identify the visual outcome and possible complications of partial transepithelial topography-guided PRK combined with collagen crosslinking in patients with keratoconus. MATERIALS AND METHODS. Twenty eyes (20 patients) were treated with partial transepithelial topography-guided PRK combined with collagen crosslinking. Patients were evaluated preoperatively for best spectacle corrected visual acuity (BSCVA), clinical signs of keratoconus via slit lamp examination, and Scheimpflug-generated corneal topography. All eyes were treated with Amaris 750s Excimer Laser and KXL system. RESULTS . Mean BCVA was improved from 20/100 to 20/25, postoperatively. Mean flat K was 46.8 ± 0.14 D preoperatively and was reduced to 45.2 ± 0.7 D postoperatively. Mean steep K was reduced from 50.2 ± 0.10 D to 47 ± 0.6 D. Total corneal astigmatism was 4.5 ± 0.14 D and decreased to 2.5 ± 0.10 D postoperatively. Average thinnest pachymetry was reduced from 465 ± 9.9 μm to 416 ± 11.3 μm. Total RMS (corneal aberrations) was 15.5 ± 7.4μm and was significantly reduced to 5.5 ± 2 μm. CONCLUSIONS. Partial transepithelial topography-guided PRK combined with collagen crosslinking can benefit patients fitting the criteria for such a procedure, by stabilising their cornea as well as improving their BSCVA.

Partial transepithelial topography-guided PRK combined with corneal collagen crosslinking in patients with keratoconus