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A high-altitude environment causes appetite loss in unacclimatised humans, leading to weight reduction. Ghrelin, cholecystokinin (CCK), and glucagon like peptide-1 (GLP-1), are gut hormones involved in the regulation of food intake and energy metabolism. The liver is an important site of metabolic regulation, and together with the gut it plays a role in food intake regulation. This study intends to study the time-dependent changes occurring in plasma gut hormones, PPARα, PPARδ, and PGC1α, in the stomach and liver during hypoxia.

endokrynologia polska

Zmiany w stężeniu greliny, CCK, GLP-1 i ekspresji receptorów aktywowanych przez proliferatory peroksysomów w szczurzym modelu anoreksji wywołanej przez hipoksję