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Changes in mucin production and dyscrinia are common features of inflammation in chronic obstructive pulmonary disease (COPD). Immunohistochemical assessment of MUC-2, MUC-3, MUC-4 expression in the integumentary epithelium, goblet cells, the epithelium of mucous glands and stroma fusiform cells of the bronchial mucosa of COPD patients during an infectious and noninfectious exacerbation was performed.

advances in respiratory medicine

The Content of Mucin MUC-2, -3 and -4 Antigens in the Bronchial Mucosa Membrane of Chronic Obstructive Pulmonary Disease Patients during Acute Exacerbation—Initial Report