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Thrombosis occurs in the coronary arteries via the activation of platelets, and leads to acute myocardial infarction and sudden death. Obovatol, a major biphenolic component of Magnolia Obovata leaves, displays anti-inflammatory and acyl Co-A cholesterol acyltrasferase inhibitory effects. The purpose of this study was to determine the effects of obovatol on thrombus formation in vivo and platelet activation in vitro and ex vivo.

Antiplatelet Activity of Obovatol, a Biphenolic Component of Magnolia Obovata, in Rat Arterial Thrombosis and Rabbit Platelet Aggregation