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Advanced glycation end products (AGE) play a key role in diabetic vascular complications, whereas matrix metalloproteinases (MMPs) and apoptosis contribute to plaque instability. This study was conducted to investigate the association of AGE-mediated MMP-9 and apoptosis with the renin-angiotensin system (RAS). We also examined the correlation between plasma HbA1c levels and plaque parameters.

Advanced Glycation End Product-Mediated Matrix Metallo-proteinase-9 and Apoptosis via Renin-Angiotensin System in Type 2 Diabetes