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The TRUTH trial demonstrated that 8-month statin therapy alters the composition of coronary artery plaque using virtual histology (VH)-intravascular ultrasound (IVUS). The extended TRUTH study was conducted to evaluate the relationship between changes in coronary atherosclerosis and mid-term clinical outcomes and identify the factors associated with cardiovascular events.

C-Reactive Protein and Future Cardiovascular Events in Statin-Treated Patients with Angina Pectoris: The Extended TRUTH Study