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Children are not young adults, and therefore require specific answers to their health problems and age-specific research strategies, which are usually hindered by the “taboo” historically observed around doing research on children. In many cases, the result has been the delay in the search for solutions, while in others it has been the use of knowledge originating from adult medicine to diagnose and treat childhood problems. Just to mention one of these situations, more than half of medications used in children have not been duly evaluated in terms of safety and effectiveness in the pediatric population. The past century witnessed a few advances, especially in relation to observational research, which was particularly helpful in the field of epidemiology. However, we had to wait until well into the 20 th century to observe the same in relation to experimental clinical research, in particular pharmacology. The first initiatives to conduct pediatric pharmacological research took place as recently as in the late 1980s, first in the United States, then in Europe and, finally, in some Latin American countries. 2

Fifty years of the Sociedad Latinoamericanade Investigación Pediátrica