English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Cholera is virulent disease that affects both children and adults and can kill within hours. It has long been, and continues to be, a global threat to public health regardless of the advancement of medical science and health care service available. In this paper we formulate and analyze a mathematical model of the dynamics and optimal con- trol strategies for cholera epidemic. We present and analyze a cholera model with controls: u1 for vaccination of the human population, u2 for treatment and u3 for health education campaigns. The basic reproductive number R0; the effective reproductive number Re; as well as disease free equilibrium and endemic equilibrium points are derived. We establish the conditions for optimal control of the cholera disease using the Pontryagin's maximum principle and simulate the model for different control strategies. The results show that vaccination and education campaigns should be applied from start of the epidemic in any community faced with cholera disease.

Modeling Optimal Control of Cholera Disease Under the Interventions of Vaccination, Treatment and Education Awareness