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Background: Zirconia ceramics have recently been widely used in dentistry because these materials are very favorable for chemical, dimensional stability, mechanical strength and hardness, Zolid FX (Ceramill Zolid FX, Amann Girrbach AG) is a type of zirconia. In this study, we have tried to measure the effects of different methods of surface preparation of full-contour restoration on the degree of material release and cellular response, so that we can recommend a method with lower tissue damage.Methods: In this study, Twenty blocks were prepared by CAD / CAM with dimensions of 5.5 mm in diameter and 3 mm in thickness and randomly divided into four groups. The laser used in this study is a co2 laser (Ultra-dream pluse, guro-gu seul, Korea). Comparison of the groups with the intact group was carried out two by two. The control group was compared by ANOVA and the groups with significant differences (with a significant percentage of 0.05) were compared by TUKEY statistical test.Conclusion and Results: Delivering one-stage, non-glazed-polished zirconium restorations can result in incompatible cellular response and is detrimental to the health of the periodontal tissue surrounding the restoration. It is also recommended that if the restoration due to the adjusting of clinician lose the glazed layer should not be delivered intact, at least prepare by polishing method, also if the laser is available in the clinic, then the surface restoration will be prepare using it, although it has not been routinely used due to lesser access to lasers in clinics.

Comparative Evaluation of Cellular Response to Three Types of Zolid Surface Full Contour: Glazing, Polishing, and CO2 Laser