English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Diabetes mellitus (DM) is a metabolic condition with chronic hyperglycemic symptoms and metabolic disorders. It is probably due to either insulin deficiency, insulin resistance or failure of β-cells of the pancreas to generate insulin, carbohydrates, fats and proteins 1. Moreover, diabetic patients reportedly have a higher incidence of peptic ulcer disease. Peptic ulcer disease and DM are two serious chronic diseases with many medicals and socioeconomic consequences 2. Researchers found that DM was independently associated with increased risk of peptic ulcer bleeding 3. Herbal medicines with antihyperglycemic activity have been used as alternative treatments of DM due to their reduced side effects and lower cost compared to synthetic hypoglycemic drugs 4. Following the World Health Organization recommendations for DM (WHO 1980), the search for safer and more effective hypoglycemic pharmaceuticals from medicinal plants has continued to be an important area of active research 5. Gleditsia triacanthos L. (Leguminosae), a 45 m long tree, is cultivated in Egypt public parks and gardens for ornamental purposes 6. Extracts and isolates from different parts of G. triacanthos have been reported to possess different pharmacological potentials such as analgesic 6, anti-oxidant 7, anti-diabetic 8, oncostatic and cytotoxic activities7, 9.

pharmacognosy journal

Characterization of Flavonoids and Saponins from Gleditsia triacanthos by LC-ESI/MS/MS Analysis: Pharmacological Assessment of the Anti-hyperglycemic and Anti-ulcerogenic Activities of G. triacanthos methanolic Fruit Extract and its n-Butanol Fraction