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Indonesia is one of the mega-biodiversity countries that is known as a storehouse of medicinal plants. There are approximately 30,000 species of flora found in Indonesia's tropical forests. About 9,600 species have been known to be medicine.1 Since ancient times, medicinal plants processed as folk remedies have been widely used by Indonesians, both in the form of fresh single, mixed, and herb that is better known as traditional medicine or herbal medicine. Since time immemorial, people have commonly used traditional medicine, so traditional medicine is relatively safe for human consumption.

Anti-inflammatory Activity of Pegagan Embun (Hydrocotyle sibthorpioides Lam.) Plant Extract on Topical Application