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Innovation of natural products for antibiotics and antioxidants is very urgent, because the emergence of antibiotic-resistant microorganisms that require inventive research and development strategies. Endophytic fungus isolated from the gall rust of F. moluccana have the ability to produce antimicrobial compounds and antioxidants. Thirty-four endophytic fungi were isolated from the gall rust of the F. moluccana, screened and evaluated for their ability to produce antimicrobial and antioxidants compounds. Antimicrobial activity was found in at least one or more pathogenic microbes (bacteria and fungi) tested. Endophytic fungal culture extract from the gall rust of the F. moluccana has the ability to inhibit B.subtilis, P. aeruginosa and E. coli.1 To further increase the production of bioactive compounds, this research is focused on isolates which in the previous studies produced the highest compound and high activity, and sought optimal fermentation conditions in production.

pharmacognosy journal

Production of Secondary Metabolites and its Antibacterial and Antioxidant Activity During the Growth Period of Endophytic Fungi Isolated from Gall Rust Sengon Plants