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Aging is a common process by which humans gradually lose skin elasticity and collagen fibers. Over the age of 20 years, aging manifestations appear as collagen content per unit area begins to decrease, there is a 1% reduction in collagen content per unit area of the skin each year.1 Skin aging is determined by a consolidation of intrinsic factors (genetics, cellular metabolism, and hormones) and extrinsic (continual light risk, pollution, ionizing radiation, chemicals, poisons). The subject of most of the research on antiaging and efforts for aesthetic-antiaging strategies related to the skin are the three main structural components of the dermis, namely collagen, elastin, and Glycosaminoglycans (GAGs).2

pharmacognosy journal

Anti-Elastase, Antioxidant, Total Phenolic and Total Flavonoid Content of Wuru Ketek (Myrica javanica Reinw. ex Bl.) from Tangkuban Perahu, West Java - Indonesia