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Basically, the main purpose of treating vaginal atrophy is to decrease symptoms.1 There are some therapies available to decrease symptoms of vaginal atrophy including hormone therapy, vaginal lubricant and vaginal estrogen.2 Food and Drug Administration (FDA) recommend estrogen treatment to cure vaginal atrophy.3 Estrogen therapy given orally or vaginally was known successfully reduces the symptoms of vaginal atrophy like dryness, sexual dysfunction and vaginal atrophy.4 Nevertheless, the long term effect of use estrogen may risk breast cancer, endometrial cancer and coronary heart disease.3

Estrogenic Effect of the Leaves from Katuk (Sauropus androgynus L. Merr) on Vaginal and Endometrial Atrophy in Perimenopausal Mice