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Quercetin is a major flavonoid in most plant extracts.5 Quercetin is known for anti-oxidant, anti-inflammatory, anti-obesity, anti-hypertensive, vasodilatory, anti-hypercholesterolemic, antiatherosclerotic, anti-bacterial, and anti-biofilm effects.6-9 However, the conventional method for extracting this flavonoid uses large volumes of organic solvent. Furthermore, this process is limited by long extraction times and low active compound levels. In ethanol extracts of mangkokan Leaf an average at 1.53%, in ethyl fractions acetate an average at 4.79%, and ethyl acetate extract at 1.64%, ethyl acetate fraction at 5.83%.2-3

Extraction of Quercetin from Nothopanax scutellarium Leaves via Ionic Liquid-based Microwave-assisted Extraction