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Cancer is the most common cause of death in Thailand, with 85,000 fatalities a year from liver and bladder, lung, colon, breast and cervical disease. Over the next 21 years, 24 million Thais are predicted to be diagnosed with cancer.1 Chemotherapy is one of the most effective treatments for prolonging the patient’s life. However, many chemotherapeutic drugs encountered reduction of therapeutic effect due to the problem of drug-resistance2 and may as well exert toxicity to normal cells leading to unpleasant side effects to the patients. These adverse sides of cancer chemotherapy prompt the continuing discovery of novel anticancer agents or alternative treatments. Microbes have so far established their candidacy as alternative anticancer treatment through the production of several bioactive compounds such as antioxidant enzymes, immune toxins, proteins, and secondary metabolites for therapeutic purposes.3

pharmacognosy journal

Cytotoxicity of Lactobacillus plantarum KK518 Isolated from Pak-Sian Dong (Thai Fermented Gynandropsis pentaphylla DC.) Against HepG2, MCF-7 and HeLa Cancer Cells