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World Allergy Organization (WAO) estimated that the prevalence of allergic diseases from the entire country's population ranges from 10 40%.1 The incidence of allergic diseases was high enough in various parts of the world, both in developed and developing countries. United Kingdom (UK) had the highest prevalence of allergic diseases in the world; more 20% of the population had one or more allergic disorders. In asthma, Scotland had the highest prevalence with 18.4%, the United Kingdom with 15.3%, Canada with 14.1%, United States with 10.9%, while Indonesia was 1.1%.2,3 In rhinitis, The International Study on Asthma and Allergies in Childhood (ISAAC), the prevalence of rhinitis symptoms in children varied between 0.8% to 14.9% at 6 -7 years old and between 1.4% to 39.7% at 13 14 years old. Indonesia was one of the countries with low prevalence, besides Albania, Romania, Georgia and Greece. Whereas the countries with high prevalence were Australia, New Zealand and the United Kingdom.4

The Extract of Kincung Flower (Etlingera elatior (Jack) R.M.Sm.) Activity to Decrease IL-4 and IgE Levels in Type I Hypersensitivity White Male Mice