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Coastal plants and sponges are marine resources that have been widely known as producers of bioactive compounds.1-3 They are rich sources of alkaloids, saponins, tannins, flavonoids, terpenoids, and glycosides1,4 many of which exhibit various bioactivities including anticancer,5 antifungal,2,3,6 antiviral,4 antioxidant7-9 and antibacterial activities.2,4,6,8,10,11 The application of antibacterial compounds from coastal plants and sponges are not only limited in medication of disease caused by human pathogenic bacteria12,13 but also have been applied to overcome the problem of fish bacterial infections.2,12

Antibacterial Activity of Coastal Plants and Marine Sponges from Kei Island Indonesia against Bacterial Fish Pathogens